Prednisone and Alcohol: Side Effects & Tips for Consumption

Prednisone is a steroid that can be used to treat different kinds of conditions like breathing problems, skin allergy, cancer, arthritis, eye problems, etc. Prednisone falls under the category of drugs known as corticosteroids. It acts by reducing the immune systems receptivity to various diseases, thereby preventing swelling and other allergic reactions. But can Prednisone and Alcohol be consumed together? Let’s find out.

They also serve the function of evening out the hormone levels in people whose adrenal glands are incapable of producing enough corticosteroids. Prednisone can be taken as a tablet or as a liquid solution and is taken directly by mouth. They are usually prescribed for short term medication, but depending on the severity of the condition, can be extended for longer periods.

One burning question that has left people scratching their heads is whether they could consume alcohol while under medication. More importantly, is such a combination safe and could they cause any harm for the rehabilitation process? This is what we will be dealing in this article and read on to find out more.

Using Prednisone

Prednisone and Alcohol

First and foremost, you should refrain from taking Prednisone if you have a fungal infection which requires oral antifungals. When visiting the doctor, inform him if you use any other medication.

Moreover, using Prednisone will lower the capability of your immunity system and you might become prone to infections. Therefore, avoid going near sick people. Also, avoid live vaccines.

Female patients should avoid taking the medication during the first trimester. This is because it might cause birth defects. Hence, inform the doctor in case you are pregnant.

When using Prednisone you must be careful of the following conditions like breathing problems, eye pain, vision problems, or changes in personality. If you experience any of the following, immediately inform your doctor.

Finally, do not stop the medication unless your doctor has asked you to. Else, it might lead to complicated results.

When should you use Prednisone?

Prednisone can be used to treat any of the following conditions.

  1. any illness that causes diarrhea;
  2. liver disease (such as cirrhosis);
  3. kidney disease;
  4. heart disease, high blood pressure, low levels of potassium in your blood;
  5. a thyroid disorder;
  6. diabetes;
  7. a history of malaria;
  8. tuberculosis;
  9. osteoporosis;
  10. glaucoma, cataracts, or herpes infection of the eyes;
  11. stomach ulcers, ulcerative colitis, or a history of stomach bleeding;
  12. a muscle disorder such as myasthenia gravis; or
  13. depression or mental illness.

You should also be aware that long term use of Prednisone might lead to Osteoporosis.

Prednisone and Alcohol

Both these substances are harmful when taken in excess. Steroids can help cure endocrine disorders for which the effect is mitigated by consuming alcohol. Alcohol is also known to cause harm to unborn children and there is a possibility that the combination would as well.

It is not easy to give a one-word answer on whether you could drink alcohol along with Prednisone. The consequences of any depend on the three factors below.

  1.  The dosage of prednisone that you are taking.
  2. The quantity of alcohol consumed by you.
  3. The duration of the treatment.

Therefore, ultimately it is your doctor who should advise you on this matter.

Prednisone and Alcohol Reaction

Some of the side effects due to Prednisone might be worsened due to the consumption of alcohol Prednisone together.

  1. Using alcohol and Prednisone together might weaken your immunity system further. Your body then becomes weak and will not be able to fight infections.
  2. They can increase the risk for developing type 2 diabetes as both of them raise the blood sugar levels.
  3. Both the substances irritate the digestive tract and can result in peptic ulcers. Therefore, it is better to avoid them.
  4. The combination can also increase the risk of Osteoporosis.
  5. Mood disorders are also a possibility when you mix them both.
  6. Also, your heartbeat might be irregular.

Besides, alcohol Prednisone will also interact with a number of other medicines. We have listed them below.

  1. Blood thinners
  2. Antifungal medications
  3. Aspirin
  4. Medications for Nausea.
  5. Medications for heartburn.
  6. Medications for seizures
  7. Drugs in the immunosuppressant class
  8. Certain antibiotics
  9. Corticosteroids
  10. Contraceptives
  11. Diuretics
  12. HIV medicines.
  13. Tranquillizers or medicines to reduce stress and depression.
  14. St. John’s Wort or herbs which act in a similar way upon the body
  15. Medicines for heart problems.
  16. Drugs for Asthma-like zafirlukast.
  17. Tobacco

Side Effects of Using Prednisone

Depending on the dosage and the duration of the meditation period, Prednisone might cause some unwanted side-effects as well.

  1. bulging eyes
  2. confusion
  3. Periods of depression.
  4. Irregular and extreme mood swings.
  5. gastrointestinal problems
  6. personality changes
  7. Inability to find sleep (Insomnia).
  8. Extreme tiredness of the body.
  9. muscle weakness
  10. Increase in weight.
  11. loss of touch with the reality
  12. Problems while breathing.
  13. signs of infection
  14. swelling of the different parts like the face, arms, hands, feet or even lower legs
  15. Short breaths.
  16. Hands shaking vigorously and uncontrollably.
  17. Issues with the vision.

Similarly, there exist side effects while consuming Methotrexate and alcohol. Therefore, it is advised to explore precautionary measures.


  1. Use prednisone after having a complete meal. In this way, the damage to your digestive system can be significantly reduced. Usings antacids are also recommended.
  2. Instead of starving yourself, consume small light meals throughout the day to keep your blood sugar at bay. Following a diabetic meal plan can also help stave off steroid-induced diabetes.
  3. Don’t overeat. Consume meals that you would normally eat. Steroids can make you feel as if you are still hungry This is just a side-effect of the medication. This may also be the reason why some people on steroids tend to gain weight.
  4. It is better to control your salt intake to stop water retention. You can find salts in foods that are canned, frozen, packaged, or even pickled. Prednisone can change your sense of taste and make you feel hungry, but you should not compensate by eating a lot of salts.
  5. Stay away from stimulants like caffeine and nicotine that can seriously affect your sleep issues worse. Cutting these out can help decrease the possibility of insomnia, which is a very common side effect of using prednisone.

Drinking one or two bottles of beer or other alcoholic drinks while using Prednisone might not significantly impact your health but the best way is to follow your doctor’s advice. After all, health is the best wealth.

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